Born in South Jamaica, Queens, Jackson began drug dealing at the age of twelve during the 1980s crack epidemic.After leaving drug dealing to pursue a rap career, he was shot at and struck by nine bullets during an incident in 2000. After releasing his album Guess Who's Back? in 2002, Jackson was discovered by rapper Eminem and signed to Interscope Records. With the help of Eminem and Dr. Dre, who produced his first major commercial successes, Jackson became one of the world's highest selling rappers. In 2003, he founded the record label G-Unit Records, which signed several successful rappers such as Young Buck, Lloyd Banks, and Tony Yayo.